According to this article http://industry.bnet.com/technology/10005104/uspto-wont-accept-upside-down-faxes-demands-resends/, the US Patent Office cannot process faxes that are received upside down. (h/t bizwriter at slashdot)
So, you’re telling me that the nameless bureaucrat who picks up the stupid faxes is too lazy to flip the freaking thing right side up, but must immediately write a form letter to announce their laziness? I certainly hope this turns out to be some crank. And I totally want my healthcare in the hands of these people.